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What is the proportion of NaCl required to render a 1.5% solution of drug isotonic with blood plasma? The freezing point of 1% w/v solution of drug is -0.122°C and that of NaCl is -0.576°C
0.65% 0.585% 0.9% 0.5%
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Which of the following drugs has both alfa1-selective and beta-blocking effects?
Labetalol Betaxolol Propranolol Timolol |
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Which of the following sympathomimetics is related to short-acting topical decongestant agents?
Xylometazoline Terbutaline Phenylephrine Norepinephrine |
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Ephedrine causes:
Miosis Bronchodilation Hypotension Bradycardia |
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Indicate the main claim for an ideal hypnotic agent:
Rapid onset and sufficient duration of action Minor effects on sleep patterns Minimal “hangover” effects All of the above |
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which of the following antitubercular drug doese not required dose adjustment in renal failure
INH ethambutol rifampicin streptomycin |
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Which of the following factors can influence the biodisposition of hypnotic agents?
Alterations in the hepatic function resulting from a disease Old age Drug-induced increases or decreases in microsomal enzyme activities All of the above |
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Which of the following effects is associated with beta3-receptor stimulation?
Lipolysis Decrease in platelet aggregation Bronchodilation Tachycardia |
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Indicate the long-acting topical decongestant agents:
Epinephrine Norepinephrine Phenylephrine Xylometazoline |
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MOA of moricizine:
prolongs APD shortens APD no change in APD calcium channel blecker |
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Indicate the sympathomimetic, which may cause hypotension, presumably because of a clonidine-like effect:
Methoxamine Phenylephrine Xylometazoline Isoproterenol |
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Epinephrine produces all of the following effects EXCEPT:
Positive inotropic and chronotropic actions on the heart (beta1 receptor) Increase peripheral resistance (alfa receptor) Predominance of alfa effects at low concentration Skeletal muscle blood vessel dilatation (beta2 receptor) |
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Decreased risk of Atherosclerosis is associated with increase in
very low density lipoproteins low density lipoproteins cholesterol high density lipoproteins |
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The principal adverse effects of phentolamine include all of the following EXCEPT:
Diarrhea Bradycardia Arrhythmias Myocardial ischemia |
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Indicate the beta1-selective antagonist:
Propranolol Metoprolol Carvedilol Sotalol |
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The risk of Digitalis toxicity is significantly increased by concomitant administration of
Triamterene Lidocaine Captopril Hydrochlorthiazide
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Indicate the drug, which is a direct-acting both alfa- and beta-receptor agonist:
Norepinephrine Methoxamine Isoproterenol Ephedrine |
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The dose related side effect of Iso nicotinamide hydralazide (INH) is
Hyper uricem Hepatotoxicity Renal toxicity Neurotoxicity |
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Norepinephrine produces:
Vasoconstriction Vasodilatation Bronchodilation Decresed potassium concentration in the plasma |
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Beta2 receptor stimulation includes all of the following effects EXCEPT:
Stimulation of renin secretion Fall of potassium concentration in plasma Relaxation of bladder, uterus Tachycardia |
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