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The mechanism of antiparasitic action of Mebendazole and thiabendazole involves
stimulation of acetylcholine receptors at neuromuscular junctions inhibition of dihydropolate reductase interference with microtubule synthesis and assembly block thiamine transport
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Isoniazid is a primary antitubercular agent that
requires pyridoxine supplementation causes ocular complications that are reversible if the drug is discontinued is ototoxic and nephrotoxic should never be used due to hepatotoxic potential
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Decreased risk of Atherosclerosis is associated with increase in
very low density lipoproteins low density lipoproteins cholesterol high density lipoproteins
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The mechanism of action of Paclitaxel is
bind to DNA through intercalation between specific bases and block the synthesis of new RNA or DNA, cause DNA strand scission mitotic spindle poison through the enhancement of tubulin polymerization competitive partial agonist œ inhibitor of estrogen and binds to estrogen receptors S-Phase specific antimetabolite that is converted by deoxykinase to the 5‘-mononuleotid
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A drug which has antipyretic, anti-inflammatroy and antiplatelet activity is
Sulfinpyrazone Aspirin Ticlopidine Acetaminophen
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A 60 year old patient presents with glaucoma. Therapy should include
Choose the correct combination, (P) topical atropine (Q) topical pilocarpine (R) oral acetazolamide (S) oral pilocarpine
P, Q Q, R R, S P, S
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Bioassays are carried out to
Measure the pharmacological activity of a drug Avoid clinical trails for new drugs Detect the impurity in a given drug Screen fro pharmacognetic influences of new drugs
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A direct way of studying idiosyncratic reactions to a given drug is by
changing the route of drug administration changing the assay method pharmacogenomics structure activity relationship studies of a family of compounds
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An example of haemopoietic growth factor is
platelet derived growth factor epidermal growth factor iron dextran erythropoietin
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Not true about tacrolimus is all except
It binds to cyclophillin It is a prodrug It activates IL-2 transcription Nephrotoxicity is a common adverse effect
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Which of the following ACE inhibitor has highest bioavailability
Captopril Enalapril Fosinopril Ramipril
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Which of the following is not a ANTIPLATELET drug
Eptifibatide Abciximab Tirofiban Aprotinin
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Which of the following is NOT an epithelial growth factor receptor inhibitor
Gefitinib Erlotinib Cetuximab Irinotecan
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which of the following antitubercular drug doese not crosses the brain blood barrier.
INH ethambutol rifampicin streptomycin
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which of the following antitubercular drug doese not required dose adjustment in renal failure
INH ethambutol rifampicin streptomycin
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Why is buprenorphine less addictive than other opioids (like fentanyl) - is it explainable by its strength of binding to the common receptor, or?
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which of the following antitubercular drug contraindicated in pragnancy.
INH ethambutol rifampicin streptomycin
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Is Phenoxyethanol harmful?
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What is the definition of “Biomedical”? What topics cover the Study of Biomedical Sciences?
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Do you know how the dose for children is being estimated based on preclinical data?
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