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Pharmacology is the branch of medicine and biology concerned with the study of drug action, where a drug can be broadly defined as any man-made, natural, or endogenous (from within body) molecule which exerts a biochemical and/or physiological effect on the cell, tissue, organ, or organism (sometimes the word pharmacon is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals.
|Compared with epinephrine, ephedrine produces all of the following features EXCEPT:
It is a direct-acting sympathomimetic
It has oral activity
It is resistant to MAO and has much longer duration of action
Its effects are similar, but it is less potent
|Indicate the barbituric acid derivative, which has 4-5 days elimination half-life:
|Which of the following topical decongestant agents is an alfa2-selective agonist?
|Which of the following sympathomimetics is preferable for the treatment of chronic orthostatic hypotension?
|Antidote of Digoxin
|Compared with epinephrine, norepinephrine produces all of the following effects EXCEPT:
Similar effects on beta1 receptors in the heart and similar potency at an alfa receptor
Decrease the mean pressure below normal before returning to the control value
Significant tissue necrosis if injected subcutaneously
Increase both diastolic and systolic blood pressure
|Isoproterenol produces all of the following effects EXCEPT:
Increase in cardiac output
Fall in diastolic and mean arterial pressure
|Indicate adrenoreceptor antagonist agents, which are used for the management of pheochromocytoma:
Selective beta2-receptor antagonists
Nonselective beta-receptor antagonists
Indirect-acting adrenoreceptor antagonist drugs
|Beta-blocking agents have all of the following effects except:
Increase plasma concentrations of HDL and decrease of VLDL
Decrease of aqueous humor prodaction
|All of the following can be used in chloroquine resistant malaria due to P. falciparum except:
|Characteristics of phentolamine include all of the following EXCEPT:
Reduction in peripheral resistance
Stimulation of responses to serotonin
Stimulation of muscarinic, H1 and H2 histamine receptors
|Drug of choice of actinimycosis
|Unless otherwise stated in the individual monograph of the pharmacopoeia, in the disintegration test for enteric coated tablets, first the dissolution is carried out in
0.1 M HCl
0.1 M HSO 2 4
|During slow wave sleep (stage 3 and 4 NREM sleep):
The secretion of adrenal steroids is at its highest
Somnambulism and nightmares occur
The secretion of somatotropin is at its lowest
|Indicate the hypnotic drug, which does not change hepatic drug-metabolizing enzyme activity?
All of the above
|Orally effective drug in candidiasis
|Which of the following agents is a beta2?selective antagonist?
|Which of the following sympathomimetics is an effective mydriatic?
|Indicate a hypnotic drug - a selective agonist at the BZ1 receptor subtype:
|Which of the following factors can influence the biodisposition of hypnotic agents?
Alterations in the hepatic function resulting from a disease
Drug-induced increases or decreases in microsomal enzyme activities
All of the above
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Latest 20 Questions
Payment of time- barred debt is:
Consideration is defined in the Indian Contract Act,1872 in: (a) Section 2(f) (b) Section 2(e) (c) Section 2(g) (d) Section 2(d)
Which of the following is not an exception to the rule, "No consideration, No contract": (a) Natural love and affection (b) Compensation for involuntary services (c) Completed gift (d) Agency
Consideration must move at the desire of: (a) The promisor (b) The promisee (c) The promisor or any other party (d) Both the promisor and the promisee
An offer which is open for acceptance over a period of time is: (a) Cross Offer (b) Counter Offer (c) Standing Offer (d) Implied Offer
Specific offer can be communicated to__________ (a) All the parties of contract (b) General public in universe (c) Specific person (d) None of the above
_________ amounts to rejection of the original offer. (a) Cross offer (b) Special offer (c) Standing offer (d) Counter offer
A advertises to sell his old car by advertising in a newspaper. This offer is caleed: (a) General Offer (b) Special Offer (c) Continuing Offer (d) None of the above
In case a counter offer is made, the original offer stands: (a) Rejected (b) Accepted automatically (c) Accepted subject to certain modifications and variations (d) None of the above
In case of unenforceable contract having some technical defect, parties (a) Can sue upon it (b) Cannot sue upon it (c) Should consider it to be illegal (d) None of the above
If entire specified goods is perished before entering into contract of sale, the contract is (a) Valid (b) Void (c) Voidable (d) Cancelled
______________ contracts are also caled contracts with executed consideration. (a) Unilateral (b) Completed (c) Bilateral (d) Executory
A offers B to supply books @ Rs 100 each but B accepts the same with condition of 10% discount. This is a case of (a) Counter Offer (b) Cross Offer (c) Specific Offer (d) General Offer
_____________ is a game of chance. (a) Conditional Contract (b) Contingent Contract (c) Wagering Contract (d) Quasi Contract
There is no binding contract in case of _______ as one's offer cannot be constructed as acceptance (a) Cross Offer (b) Standing Offer (c) Counter Offer (d) Special Offer
An offer is made with an intention to have negotiation from other party. This type of offer is: (a) Invitation to offer (b) Valid offer (c) Voidable (d) None of the above
When an offer is made to the world at large, it is ____________ offer. (a) Counter (b) Special (c) General (d) None of the above
Implied contract even if not in writing or express words is perfectly _______________ if all the conditions are satisfied:- (a) Void (b) Voidable (c) Valid (d) Illegal
A specific offer can be accepted by ___________. (a) Any person (b) Any friend to offeror (c) The person to whom it is made (d) Any friend of offeree
An agreement toput a fire on a person's car is a ______: (a) Legal (b) Voidable (c) Valid (d) Illegal