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Select a hypnotic drug, which is an imidazopyridine derivative:
Pentobarbital Temazepam Zolpidem Chloral hydrate |
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Epinephrine produces all of the following effects EXCEPT:
Decrease in oxygen consumption Bronchodilation Hyperglycemia Mydriasis |
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Hypnotic drugs are used to treat:
Psychosis Sleep disorders Narcolepsy Parkinsonian disorders |
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Which of the following is not a ANTIPLATELET drug
Eptifibatide Abciximab Tirofiban Aprotinin |
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Dorzolamide MOA is:
topical carbonic anhydrase inhibitor systemic carbonic anhydrase inhibitor cytochrome P-450 inhibitor cytochrome P-450 inducer |
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Indicate the beta adrenoreceptor antagonist, which has partial beta–agonist activity:
Propranolol Metoprolol Pindolol Betaxolol |
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Characteristics of alfa-receptor antagonists include all of the following EXCEPT:
They cause a fall in peripheral resistance and blood pressure They cause epinephrine reversal (convert a pressor response to a depressor response) Bronchospasm They may cause postural hypotension and reflex tachycardia |
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A drug which causes pink to brownish skin pigmentation within a few weeks of the initiation of therapy is
Itraconazole Clofazimine Lomefloxacin Neomycin
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Indicate the irreversible alfa receptor antagonist:
Tolazoline Labetalol Prazosin Phenoxybenzamine |
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Digoxin act by inhibiting
Na K ATPase Ca channels K channels Adenyl cyclase |
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Compared with epinephrine, norepinephrine produces all of the following effects EXCEPT:
Similar effects on beta1 receptors in the heart and similar potency at an alfa receptor Decrease the mean pressure below normal before returning to the control value Significant tissue necrosis if injected subcutaneously Increase both diastolic and systolic blood pressure |
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Characteristics of phentolamine include all of the following EXCEPT:
Reduction in peripheral resistance Stimulation of responses to serotonin Tachycardia Stimulation of muscarinic, H1 and H2 histamine receptors |
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Unless otherwise stated in the individual monograph of the pharmacopoeia, in the disintegration test for enteric coated tablets, first the dissolution is carried out in
0.1 M HCl phosphate buffer water 0.1 M HSO 2 4 |
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Indicate the mechanism of barbiturate action (at hypnotic doses):
Increasing the duration of the GABA-gated Cl- channel openings Directly activating the chloride channels Increasing the frequency of Cl- channel opening events All of the above |
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Plasma half life of drugs
Maximum effective dose of drug maximum lethal effect potency of drug Dose frequency interval |
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GTN is given sublingually why?
To avoid first pass metabolism Rapid effect Gastric irritation To avoid side effects |
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Which of the following barbiturates is an ultra-short-acting drug?
Secobarbital Amobarbital Thiopental Phenobarbital |
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Metronidazole is a
Luminal amoebicide Tissue amoebicide Both None of these |
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Hepatic microsomal drug-metabolizing enzyme induction leads to:
Barbiturate tolerance Cumulative effects Development of physical dependence “hangover” effects |
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Drug of choice for typhoid fever
Ciprofloxacin Ampicillin Chloremphenicol Tetracycline |
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