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	Microbiology Interview Questions & Answers Below we have listed all the Microbiology Interview Questions and answers. Feel free to comment on any Microbiology Interview Questions or answer by the comment feature available on the page. To buy an eBook containing 30,000 Interview Questions, with Answers, Click Here. View All Microbiology Interview Questions & Answers - Exam Mode / Learning Mode
Microbiology Interview Questions & Answers
Microbiology is the study of organisms, most of which are too small to be seen with the naked eye, including bacteria, algae, protozoa, and fungi, as well as acellular agents, such as viruses and prions. Eukaryotic micro-organisms possess membrane-bound cell organelles and include fungi and protists, whereas prokaryotic organisms—all of which are microorganisms—are conventionally classified as lacking membrane-bound organelles and include eubacteria and archaebacteria. Microbiologists traditionally relied on culture, staining, and microscopy. However, less than 1% of the microorganisms present in common environments can be cultured in isolation using current means. Microbiologists often rely on extraction or detection of nucleic acid, either DNA or RNA sequences.

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In the 1920s, the Rockefeller Foundation funded a physician to go throughout the Pacific Islands to decrease the incidence of hookworm. Each of the following but one would help decrease the incidence of this disease. Which one would not make any change in incidence of Ancylostoma duodenale or Necator americanus? A. Wearing shoes B. Washing hands after using the bathroom C. Using latrines for defecation D. Treating those found to be infected E. Establishing sewage treatment facilities		View Answer
The most likely infection to occur following exposure to Sporothrix is? A. A urinary tract infection B. Pneumonia C. Meningitis D. An ulcerating skin lesion		View Answer
Characteristics of a bacterial capsule include? A. All bacteria have one B. It is composed of peptidoglycan C. It is an important mechanism for protecting a bacteria against ingestion by PMNs D. It is what causes the gram stain reaction		View Answer
A 30-year-old patient comes to clinic complaining of a three-week history of cough. He started with a runny nose, fever and sneezing for a few days followed by a dramatic cough that keeps him up at night. He complains of episodes of coughing where he will have fits of coughing with 10-15 coughs during one exhalation to the point that he is afraid that he will never be able to take in a breath. These coughing episodes are so severe that his ribs are extremely sore. An organism you should consider would be? A. Staph aureus B. Tuberculosis C. Bordetella pertussis D. Haemophilus influenzae		View Answer
The pathogenesis of dengue hemorrhagic shock syndrome is distinguished from that of uncomplicated dengue by? A. Excitotoxic injury of neurons B. Development of dengue virus meningiits C. Immune enhancement of infection D. Neurotropic spread of virus		View Answer
The infection most often associated with Cryptococcus neoformans is? A. Septic arthritis B. Sinusitis C. Pneumonia D. Meningitis		View Answer
One of the characteristics of HIV infection is that? A. The virus multiplies slowly with a half-life of weeks matching the slow rate of disease progression B. There is rapid dissemination of virus within the first few weeks of infection to all tissues C. In early infection the virus is most actively multiplying within the bloodstream D. There is little if any immune response to HIV infection, and that is why this infection is so overwhelming		View Answer
A cytolytic virus would be expected to cause cytopathic effect in cell culture? A. True B. False		View Answer
HIV reverse transcriptase, a critical target in modern antiretroviral chemotherapy, performs which critical function for the virus? A. Cleaves polyprotein precursor leading to functional assembly of viral core B. Cleaves sialic acid residue from glycoprotein permitting attachment and entry into cell C. Transcribes RNA into DNA D. Activates 2', 5’ oligoadenylate synthetase		View Answer
A 15 year old boy comes in to clinic with pain in his right ear. He is on his school swim team and spends about 2 hours per day in the pool. Along with the pain in his ear, he has watery drainage coming from the ear canal. On exam his vital signs are normal, and he appears healthy, but his left external ear looks quite red and there is copious watery, slightly green drainage coming from the ear. The organism mostly likely causing this is? A. Staph aureus B. Viridans group streptococci C. Streptococcus pneumoniae D. Pseudomonas aeruginosa		View Answer
HIV is the same as? A. HTLV III B. HTLV II C. HTLV I D. None of the above		View Answer
Which of the following diseases are not transmitted by ticks? A. Ulceroglandular tularemia B. Bubonic plague C. Relapsing fever D. Lyme disease		View Answer
On the same day the clinical laboratory identifies two strains of the same bacterial species. One of these strains has pili on the surface; the other does not. In terms of the clinical status of the two patients it is likely that? A. Patient with the piliated strain is ill, the other patient is not B. Patient with the piliated strain is not ill, the other patient is C. Both patients are ill since pili do not correlate with virulence D. Patient with the piliated strain is a child, the other patient is an adult		View Answer
Which of the following is true regarding Rickettsia rickettsii? A. Highest attack rates occur in Colorado and Utah B. It can be transmitted by flying squirrels C. Sheep and cattle are important reservoirs D. It is transmitted by ticks		View Answer
A 4th year medical student from the UofU traveled to Northern Ghana during an international rotation to Accra. He was fortunate enough to see a patient with Dracunculus medinensis in which they were extracting a worm from his leg onto a pencil. This parasite is being eradicated from the world. Which of the following is least likely to help rid the world of Dracunculus medinensis? A. Boiling surface water before drinking it B. Using a coffee filter or shirt to filter out copepods before drinking surface water C. Treating of sewage before it enters fresh surface water D. Preventing persons suspected of having Dracunculus from wading in the drinking water E. Treating ponds used for drinking water with insecticide		View Answer
A physician calls from an outlying hospital to report that his patient has passed a large, white, round worm with pointed ends that is about 8 inches long. He is concerned this could be Echinococcus but the only parasite that matches this description is Ascaris lumbricoides. Which of the following is false regarding Ascaris lumbricoides? A. Most infected humans are asymptomatic B. Large numbers of larvae passing through the lung can cause asthma type symptoms C. Large numbers of adult worms in the gut can cause obstruction D. The fertilized unembryonated egg passed in the stool requires a period of time to embryonate before it becomes infectious E. Heavy infection has been associated with rectal prolapse		View Answer
A 74-year old World War II Veteran who was a prisoner of war in the Philippines is admitted to the VAH with a Group A-Streptococcal cellulitis resulting from massive swelling of both lower legs from elephantiasis. Which of the following is false regarding elephantiasis caused by Wuchereria bancrofti? A. If these infections are not treated early they rapidly progress to massive swelling of the involved lymphatic drainage area B. It is transmitted to humans by the mosquito C. Humans are the definitive host D. The microfilaria in the blood stream of man can be transfused to another person without establishing a new infection E. The adult organisms live in the lymphatic channels of man and can result in scarring of the Lymphatic channels		View Answer
The single most important characteristic of diarrhea caused by Vibrio cholera is? A. Profound watery diarrhea B. Severe abdominal pain C. Massive bloody diarrhea D. Renal insufficiency		View Answer
An important characteristic of mycobacteria is that they are? * A. Gram negative B. Rapid growing (doubling time 15 minutes) C. Acid fast D. Alpha hemolytic		View Answer
Each of the following statements (except one) is true regarding malaria. Which one is false? A. Once someone has malaria infection, they will have it for the rest of their life in spite of treatment B. All persons who contract P. vivax malaria have Duffy Antigen present on their red blood cells C. Persons with sickle cell trait or disease are more resistant to serious malaria D. Schuffner's dots in red cell cytoplasm are most consistent with P. vivax or ovale malaria E. One way to help diagnose P. malariae is to carefully record the pattern of symptoms since it is the only species to have a 72 hour interval of symptoms		View Answer