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Pharmacology Interview Questions & Answers

Below we have listed all the Pharmacology Interview Questions and answers. Feel free to comment on any Pharmacology Interview Questions or answer by the comment feature available on the page.

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Pharmacology Interview Questions & Answers

Pharmacology is the branch of medicine and biology concerned with the study of drug action, where a drug can be broadly defined as any man-made, natural, or endogenous (from within body) molecule which exerts a biochemical and/or physiological effect on the cell, tissue, organ, or organism (sometimes the word pharmacon is used as a term to encompass these endogenous and exogenous bioactive species). More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. If substances have medicinal properties, they are considered pharmaceuticals.

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Which of the following statements is correct for zolpidem?

Causes minor effects on sleep patterns
The risk of development of tolerance and dependence is less than with the use of hypnotic benzodiazepines
Has minimal muscle relaxing and anticonvulsant effects
All of the above
0.3 Rating
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Which agent exerts hypnotic activity with minimal muscle relaxing and anticonvulsant effects?

Flurazepam
Triazolam
Zaleplon
None of the above
0.3 Rating
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2-iminothiazolidine is treated with phenyloxirane to get a drug used in roundworm infection is

piperazine
tetramisole
thiabendazole
levamisole
0.3 Rating
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A new drug delivery system which is composed of phospholipids that spontaneously form a multilamellar concentric bilayer vesicles with layers of aqueous media separating the lipid layers is

prodrugs
liposomes
osmotic pumps
nanoparticles
0.2 Rating
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Unless otherwise stated in the individual monograph of the pharmacopoeia, in the disintegration test for enteric coated tablets, first the dissolution is carried out in

0.1 M HCl
phosphate buffer
water
0.1 M HSO 2 4
0.2 Rating
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What is the proportion of NaCl required to render a 1.5% solution of drug isotonic with blood plasma? The freezing point of 1% w/v solution of drug is -0.122°C and that of NaCl is -0.576°C

0.65%
0.585%
0.9%
0.5%
0.3 Rating
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The mechanism of antiparasitic action of Mebendazole and thiabendazole involves

stimulation of acetylcholine receptors at neuromuscular junctions
inhibition of dihydropolate reductase
interference with microtubule synthesis and assembly
block thiamine transport
0.2 Rating
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Isoniazid is a primary antitubercular agent that

requires pyridoxine supplementation
causes ocular complications that are reversible if the drug is discontinued
is ototoxic and nephrotoxic
should never be used due to hepatotoxic potential
0.3 Rating
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Decreased risk of Atherosclerosis is associated with increase in

very low density lipoproteins
low density lipoproteins
cholesterol
high density lipoproteins
0.3 Rating
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The mechanism of action of Paclitaxel is

bind to DNA through intercalation between specific bases and block the synthesis of new RNA or DNA, cause DNA strand scission
mitotic spindle poison through the enhancement of tubulin polymerization
competitive partial agonist œ inhibitor of estrogen and binds to estrogen receptors
S-Phase specific antimetabolite that is converted by deoxykinase to the 5‘-mononuleotid
0.2 Rating
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A drug which has antipyretic, anti-inflammatroy and antiplatelet activity is

Sulfinpyrazone
Aspirin
Ticlopidine
Acetaminophen
0.2 Rating
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A 60 year old patient presents with glaucoma. Therapy should include



Choose the correct combination,
(P) topical atropine
(Q) topical pilocarpine
(R) oral acetazolamide
(S) oral pilocarpine

P, Q
Q, R
R, S
P, S
0.3 Rating
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Bioassays are carried out to

Measure the pharmacological activity of a drug
Avoid clinical trails for new drugs
Detect the impurity in a given drug
Screen fro pharmacognetic influences of new drugs
0.2 Rating
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A direct way of studying idiosyncratic reactions to a given drug is by

changing the route of drug administration
changing the assay method
pharmacogenomics
structure activity relationship studies of a family of compounds
0.3 Rating
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An example of haemopoietic growth factor is

platelet derived growth factor
epidermal growth factor
iron dextran
erythropoietin
0.3 Rating
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Not true about tacrolimus is all except

It binds to cyclophillin
It is a prodrug
It activates IL-2 transcription
Nephrotoxicity is a common adverse effect
0.3 Rating
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Which of the following ACE inhibitor has highest bioavailability

Captopril
Enalapril
Fosinopril
Ramipril
0.2 Rating
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Which of the following is not a ANTIPLATELET drug

Eptifibatide
Abciximab
Tirofiban
Aprotinin
0.2 Rating
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Which of the following is NOT an epithelial growth factor receptor inhibitor

Gefitinib
Erlotinib
Cetuximab
Irinotecan
0.2 Rating
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which of the following antitubercular drug doese not crosses the brain blood barrier.

INH
ethambutol
rifampicin
streptomycin
0.3 Rating
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Latest 20 Questions
Payment of time- barred debt is: (a) Valid (b) Void (c) Illegal (d) Voidable
Consideration is defined in the Indian Contract Act,1872 in: (a) Section 2(f) (b) Section 2(e) (c) Section 2(g) (d) Section 2(d)
Which of the following is not an exception to the rule, "No consideration, No contract": (a) Natural love and affection (b) Compensation for involuntary services (c) Completed gift (d) Agency
Consideration must move at the desire of: (a) The promisor (b) The promisee (c) The promisor or any other party (d) Both the promisor and the promisee
An offer which is open for acceptance over a period of time is: (a) Cross Offer (b) Counter Offer (c) Standing Offer (d) Implied Offer
Specific offer can be communicated to__________ (a) All the parties of contract (b) General public in universe (c) Specific person (d) None of the above
_________ amounts to rejection of the original offer. (a) Cross offer (b) Special offer (c) Standing offer (d) Counter offer
A advertises to sell his old car by advertising in a newspaper. This offer is caleed: (a) General Offer (b) Special Offer (c) Continuing Offer (d) None of the above
In case a counter offer is made, the original offer stands: (a) Rejected (b) Accepted automatically (c) Accepted subject to certain modifications and variations (d) None of the above
In case of unenforceable contract having some technical defect, parties (a) Can sue upon it (b) Cannot sue upon it (c) Should consider it to be illegal (d) None of the above
If entire specified goods is perished before entering into contract of sale, the contract is (a) Valid (b) Void (c) Voidable (d) Cancelled
______________ contracts are also caled contracts with executed consideration. (a) Unilateral (b) Completed (c) Bilateral (d) Executory
A offers B to supply books @ Rs 100 each but B accepts the same with condition of 10% discount. This is a case of (a) Counter Offer (b) Cross Offer (c) Specific Offer (d) General Offer
_____________ is a game of chance. (a) Conditional Contract (b) Contingent Contract (c) Wagering Contract (d) Quasi Contract
There is no binding contract in case of _______ as one's offer cannot be constructed as acceptance (a) Cross Offer (b) Standing Offer (c) Counter Offer (d) Special Offer
An offer is made with an intention to have negotiation from other party. This type of offer is: (a) Invitation to offer (b) Valid offer (c) Voidable (d) None of the above
When an offer is made to the world at large, it is ____________ offer. (a) Counter (b) Special (c) General (d) None of the above
Implied contract even if not in writing or express words is perfectly _______________ if all the conditions are satisfied:- (a) Void (b) Voidable (c) Valid (d) Illegal
A specific offer can be accepted by ___________. (a) Any person (b) Any friend to offeror (c) The person to whom it is made (d) Any friend of offeree
An agreement toput a fire on a person's car is a ______: (a) Legal (b) Voidable (c) Valid (d) Illegal



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