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Physiology Interview Questions & Answers - Learning Mode

Physiology Interview Questions & Answers - Learning Mode

Physiology is the study of normal function within living creatures. It is a sub-section of biology, covering a myriad of topics including organs, anatomy, cells, biological compounds and how they interact together to make life possible. Physiology is the study of how molecules, cells and organs interact to form a whole being. The work of Physiological Society Members, advancing our knowledge of biological systems, is essential to the development of new treatments for disease.

Try Physiology Interview Questions & Answers - Exam Mode


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Physiology Interview Questions & Answers - Learning Mode
Try Physiology Interview Questions & Answers - Exam Mode
Question: What is the order of C-H bond length in C2H6 and C2H4 and C2H2?

Answer: c2h6>c2h4 >c2h2 Source:
Question: What would an inhalation, ingestion exposure as well as to the eyes of Butane, Diethylene glycol monobutyl ether, Monoethanolamine (MEA), & Sodium Hydroxide do to the human body?

Answer: Sodium hydroxide is a very caustic substance - severe burns on skin contact, can cause severe eye irritation and burning - can severely damage surface of eye causing blindness (permanent), severe burring on ingestion and inhalation.

Butane is a gas - it is very toxic if inhaled - acts like an anesthetic - can stop person breathing very quickly.

Diethyleneglycol monobutyl ether is less acutely toxic but does have long-term toxicity on various organs. Source:
Question: Does the length of the line change firing rates for simple and complex cells or does firing only change with orientation of the cells?

Answer: The cell would fire more for a line that fills its receptive field than for a shorter line. But unlike end stopped cells, it will not fire less for a very long line that extends beyond the receptive field. Source:
Question: IN XeF4, the bond angle between F-Xe-F is _________.

Answer: 90 degrees Source:
Question: How is the calculation derived for a drug to be bioequivalent with other? On which base the limit is fixed as 80-120% for a drug to be bioequivalent. What is meant by 90% confidential interval?

Answer: To be "bioequivalent" two preparations or drugs need to give the same biological effect.

The usual "experimental error" put on this is 20% - thus, 80-120% is considered "bioequivalent.?

90 percentage confidence interval means that statistically it is 90% certain that the results are equivalent.
Question: Define bond angle.

Answer: The angle between the lines joining the nuclei of the bonded atom with a central atom is called bond angle.
Question: How do you know which ganglion cells activities increase or decrease at the edge? On the web one ganglion cell increasing activity at the edge and one decreases, but how can you tell?

Answer: The receptive fields of two on center ganglion cells are shown. In the previous diagram we saw that if all the receptive field were in the light or the dark there is little change in activity. This is because only the only part in the light is part of the inhibitory surround. The one on the top increases its activity. This is because only the only part not in the light is part of the inhibitory surround. Thus there is less inhibition of this cell. Source:
Question: When we do liquid extraction, what is the effect of adding 10%acid or any base and how do we know which has to be added and up to which concentration or micro liter level can we add such buffers? If any gel formation occurs at the time of extraction, how will it affect the analysis? Shall we continue the extraction with the same or should we drop that method?

Answer: The idea of adding acid/base is to change the lipid (and therefore organic solvent) solubility of the components you want to extract.

For example, a fatty acid is more soluble in water as a salt (and, thus, in basic conditions) whereas it is largely insoluble in water in its uncharged state (in acid conditions). So adding acid to the solution of fatty acid salt in water will render it water-insoluble and, thus, move it from the water to the organic solvent.

This is a standard extra Source:
Question: What are the units of bond length?

Answer: The intermolecular distance between the bonded atoms in a molecule is called bond length and the units are Angstrom units (A0)
Question: Tell us about some drugs that can cross the blood brain barrier?

Answer: Any drug that is designed to be given orally, i.m. s.c. or i.v. and acts on the brain MUST cross the blood-brain barrier.

E.g. Opiates, anxiolytics, SSRI's, anti-psychotics

Drug needs to be lipid (fat) soluble to cross the BBB.
Question: How is the concentration of drugs in human plasma defined?

Answer: Some drugs bind extensively to plasma proteins (Warfarin binds 99%) whereas others have virtually no binding.

Extraction depends on the type of drug - there are different standard techniques for acidic, basic, and neutral drugs - and, indeed, some drugs need specific extraction techniques.

It is important for you doing bioequivalence studies to know exactly the proportion of drug extracted but such controls are again specific for each drug and use specific marker compounds.


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Latest 20 Questions
Payment of time- barred debt is: (a) Valid (b) Void (c) Illegal (d) Voidable
Consideration is defined in the Indian Contract Act,1872 in: (a) Section 2(f) (b) Section 2(e) (c) Section 2(g) (d) Section 2(d)
Which of the following is not an exception to the rule, "No consideration, No contract": (a) Natural love and affection (b) Compensation for involuntary services (c) Completed gift (d) Agency
Consideration must move at the desire of: (a) The promisor (b) The promisee (c) The promisor or any other party (d) Both the promisor and the promisee
An offer which is open for acceptance over a period of time is: (a) Cross Offer (b) Counter Offer (c) Standing Offer (d) Implied Offer
Specific offer can be communicated to__________ (a) All the parties of contract (b) General public in universe (c) Specific person (d) None of the above
_________ amounts to rejection of the original offer. (a) Cross offer (b) Special offer (c) Standing offer (d) Counter offer
A advertises to sell his old car by advertising in a newspaper. This offer is caleed: (a) General Offer (b) Special Offer (c) Continuing Offer (d) None of the above
In case a counter offer is made, the original offer stands: (a) Rejected (b) Accepted automatically (c) Accepted subject to certain modifications and variations (d) None of the above
In case of unenforceable contract having some technical defect, parties (a) Can sue upon it (b) Cannot sue upon it (c) Should consider it to be illegal (d) None of the above
If entire specified goods is perished before entering into contract of sale, the contract is (a) Valid (b) Void (c) Voidable (d) Cancelled
______________ contracts are also caled contracts with executed consideration. (a) Unilateral (b) Completed (c) Bilateral (d) Executory
A offers B to supply books @ Rs 100 each but B accepts the same with condition of 10% discount. This is a case of (a) Counter Offer (b) Cross Offer (c) Specific Offer (d) General Offer
_____________ is a game of chance. (a) Conditional Contract (b) Contingent Contract (c) Wagering Contract (d) Quasi Contract
There is no binding contract in case of _______ as one's offer cannot be constructed as acceptance (a) Cross Offer (b) Standing Offer (c) Counter Offer (d) Special Offer
An offer is made with an intention to have negotiation from other party. This type of offer is: (a) Invitation to offer (b) Valid offer (c) Voidable (d) None of the above
When an offer is made to the world at large, it is ____________ offer. (a) Counter (b) Special (c) General (d) None of the above
Implied contract even if not in writing or express words is perfectly _______________ if all the conditions are satisfied:- (a) Void (b) Voidable (c) Valid (d) Illegal
A specific offer can be accepted by ___________. (a) Any person (b) Any friend to offeror (c) The person to whom it is made (d) Any friend of offeree
An agreement toput a fire on a person's car is a ______: (a) Legal (b) Voidable (c) Valid (d) Illegal
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