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  • INTERVIEW QUESTIONS CHEMICAL ENGINEERING DETAILS
    Question :
    How can separation of chiral chemicals affect the chemical and/or pharmaceutical industries?
    Category Chemical Engineering Interview Questions
    Rating (0.2) By 14 users
    Added on 6/18/2011
    Views 240
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    Answers:

    This enantiomers (left [S] or right [R] oriented) versions of the same compound can have very different properties; this development has been significant particularly in the pharmaceutical industry. For example, the drug Seldane is a racemic mixture of both S and R versions of the drug's molecules. Through chiral separation technology, Hoechst was able to bring the drug Allegra to market in only 3 years (far less time than is usually necessary). Hoechst was able to bypass toxicity testing because Allegra is a single chiral form of its molecule. By chiral separation, the most of the side effects of Seldane were avoided in Allegra.



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