There are a couple of things to recommend: 1. Try replacing the batteries in the mouse if it is wireless. 2. Try removing the mouse ball and cleaning the rollers inside the mouse with a Q-tip. Often that residue is quite sticky. They sell kits with a "velcro" ball you clean the rollers with by putting it in place of the regular ball. 3. If that doesn't fix the problem, buy a new mouse. Optical mice don't have balls. 4. If that doesn't resolve it, you may need to hire a technicians to trouble shoot the problem.