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Question: Compared with phentolamine, prazosin has all of the following features EXCEPT:

Irreversible blockade of alfa receptors
Highly selective for alfa1 receptors
The relative absence of tachycardia
Persistent block of alfa1 receptors

Answer: Irreversible blockade of alfa receptors

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Question: Compared with phentolamine, prazosin has all of the following features EXCEPT:

Irreversible blockade of alfa receptors
Highly selective for alfa1 receptors
The relative absence of tachycardia
Persistent block of alfa1 receptors


Answer:

Irreversible blockade of alfa receptors Source: CoolInterview.com



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Related Questions
View Answer
Which of the following statements is not correct?

There are at least three subtypes of alfa1 receptors, designated alfa1a, alfa1b and alfa1d
ALFA1a subtype mediates prostate smooth muscle contraction
ALFA1b subtype mediates vascular smooth muscle contraction
ALFA1a subtype mediates both vascular and prostate smooth muscle contraction
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Indicate an alfa1 adrenoreceptor antagonist, which has great selectivity for alfa1a subtype:

Prazosin
Tamsulosin
Phenoxybenzamine
Phentolamine
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Subtype-selective alfa1 receptor antagonists such as tamsulosin, terazosin, alfusosin are efficacious in:

Hyperthyroidism
Cardiac arrhythmias
Benign prostatic hyperplasia (BPH)
Asthma
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. Indicate an alfa receptor antagonist, which is an efficacious drug in the treatment of mild to moderate systemic
hypertension:

Phentolamine
Tolazoline
Ergotamine
Prazosin
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Beta-blocking drugs-induced chronically lower blood pressure may be associated with theirs effects on:

The heart
The blood vessels
The renin-angiotensin system
All of the above
View Answer
Characteristics of beta-blocking agents include all of the following EXCEPT:

They occupy beta receptors and competitively reduce receptor occupancy by catecholamines or other beta agonists
They do not cause hypotension in individuals with normal blood pressure
They induce depression and depleted stores of catecholamines
They can cause blockade in the atrioventricular node
View Answer
Beta-receptor antagonists have all of the following cardiovascular effects EXCEPT:

The negative inotropic and chronotropic effects
Acute effects of these drugs include a fall in peripheral resistance
Vasoconstriction
Reduction of the release of renin
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Beta-blocking agents have all of the following effects except:

Increase plasma concentrations of HDL and decrease of VLDL
Bronchoconstriction
Decrease of aqueous humor prodaction
“membrane-stabilizing” action
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Beta-receptor antagonists cause :

Stimulation of lipolysis
Stimulation of gluconeogenesis
Inhibition of glycogenolysis
Stimulation of insulin secretion
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Propranolol-induced adverse effects include all of the following EXCEPT:

Bronchoconstriction
“supersensitivity” of beta-adrenergic receptors (rapid withdrawal)
Hyperglycemia
Sedation, sleep disturbances, depression and sexual dysfunction
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Propranolol is used in the treatment all of the following diseases EXCEPT:

Cardiovascular diseases
Hyperthyroidism
Migraine headache
Bronchial asthma
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Metoprolol and atenolol are the :

Are members of the beta1-selective group
Are nonselective beta antagonists
Have intrinsic sympathomimetic activity
Have an anesthetic action
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Which of the following beta receptor antagonists is preferable in patients with asthma, diabetes or peripheral vascular
diseases?

Propranolol
Metoprolol
Nadolol
Timolol
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Indicate a beta receptor antagonist, which has very long duration of action:

Metoprolol
Propranolol
Nadolol
Pindolol
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Indicate a beta1-selective receptor antagonist, which has very long duration of action:

Betaxolol
Sotalol
Nadolol
Metoprolol
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Which of the following drugs is a nonselective beta-blocker without intrinsic sympathomimetic or local anesthetic activity
and used for the treatment of life-threatening ventricular arrhythmias?

Propranolol
Oxprenolol
Sotalol
Atenolol
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Indicate a beta receptor antagonist with intrinsic sympathomimetic activity:

Propranolol
Oxprenolol
Metoprolol
Carvedilol
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Pindolol, oxprenolol have all of the following properties EXCEPT:

They are nonselective beta antagonists
They have no partial agonist activity
They are less likely to cause bradycardia and abnormalities in plasma lipids
They are effective in hypertension and angina
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Which of the following drugs has both alfa1-selective and beta-blocking effects?

Labetalol
Betaxolol
Propranolol
Timolol
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Characteristics of carvedilol include all of the following EXCEPT:

It is a beta1-selective antagonist
It has both alfa1-selective and beta-blocking effects
It attenuates oxygen free radical-initiated lipid peroxidation
It inhibits vascular smooth muscle mitogenesis
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