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Indicate a beta receptor antagonist with intrinsic sympathomimetic activity:
Propranolol Oxprenolol Metoprolol Carvedilol
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Pindolol, oxprenolol have all of the following properties EXCEPT:
They are nonselective beta antagonists They have no partial agonist activity They are less likely to cause bradycardia and abnormalities in plasma lipids They are effective in hypertension and angina
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Which of the following drugs has both alfa1-selective and beta-blocking effects?
Labetalol Betaxolol Propranolol Timolol
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Characteristics of carvedilol include all of the following EXCEPT:
It is a beta1-selective antagonist It has both alfa1-selective and beta-blocking effects It attenuates oxygen free radical-initiated lipid peroxidation It inhibits vascular smooth muscle mitogenesis
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Indicate the adrenoreceptor antagonist drug, which is a rauwolfia alkaloid:
Prazosin Propranolol Reserpine Phentolamine
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Characteristics of reserpine include all of the following EXCEPT:
It inhibits the uptake of norepinephrine into vesicles and MAO It decreases cardiac output, peripheral resistance and inhibits pressor reflexes It may cause a transient sympathomimetic effect It depletes stores of catecholamines and serotonin in the brain
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Indicate a beta-blocker, which is particularly efficacious in thyroid storm:
Pindolol Sotalol Phentolamine Propranolol
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Beta-receptor blocking drugs are used in the treatment all of the following diseases EXCEPT:
Hypertension, ischemic heart disease, cardiac arrhythmias Glaucoma Pheochromocytoma Hyperthyroidism
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Beta-blocker-induced adverse effects include all of the following EXCEPT:
Bronchoconstriction Depression of myocardial contractility and excitability “supersensitivity” of beta-receptors associated with rapid withdrawal of drugs Hyperglycemia
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Hypnotic drugs are used to treat:
Psychosis Sleep disorders Narcolepsy Parkinsonian disorders
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Hypnotic drugs should:
Reduce anxiety and exert a calming effect Induce absence of sensation Produce drowsiness, encourage the onset and maintenance of sleep Prevent mood swings in patients with bipolar affective disorders
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Which of the following chemical agents are used in the treatment of insomnia?
Benzodiazepines Imidazopyridines Barbiturates All of the above
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Select a hypnotic drug, which is a benzodiazepine derivative:
Zolpidem Flurazepam Secobarbital Phenobarbitone
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Which is a hypnotic agent – a barbituric acid derivative:
Flurazepam Zaleplon Thyopental Triazolam
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Select a hypnotic drug, which is an imidazopyridine derivative:
Pentobarbital Temazepam Zolpidem Chloral hydrate
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Which of the following hypnotic agents is absorbed slowly?
Phenobarbital Flurazepam Triazolam Temazepam
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Which of the following barbiturates is an ultra-short-acting drug?
Secobarbital Amobarbital Thiopental Phenobarbital
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Indicate the barbituric acid derivative, which has 4-5 days elimination half-life:
Secobarbital Thiopental Phenobarbital Amobarbital
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Indicate the hypnotic benzodiazepine, which has the shortest elimination half-life:
Temazepam Triazolam Flurazepam Diazepam
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Which of the following hypnotic drugs is more likely to cause cumulative and residual effects?
Zolpidem Temazepam Phenobarbital Triazolam
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